Heyuan Bio – Medical Collagen Hyaluronate
Heyuan Bio – Medical Collagen Hyaluronate
He Yuan Biotechnology (Ezhou) Co., Ltd.
He Yuan Biotechnology (Ezhou) Co., Ltd. (hereinafter referred to as “He Yuan Bio”) is a core subsidiary of the Bebevisa Group, established in 2025 within the China (Ezhou) Cross-border E-commerce Industrial Park as part of the group’s global strategic expansion.
Leveraging nearly 15 years of Bebevisa’s deep expertise in biomaterials, biodegradable raw materials, and medical devices, He Yuan Bio is a tech-driven foreign-trade enterprise integrating R&D, production, cross-border sales, brand incubation, and industrial transformation. Its core focus includes anti-HPV bioprotein dressings, medical biomaterials, disinfection products, and hygiene supplies.
Mission & Core Expertise
Driven by the mission to “block virus transmission and protect global health,” He Yuan Bio specializes in HPV infection intervention, vaginal microecological regulation, and skin/mucosal repair.
Its flagship product, the Anti-HPV Bioprotein Dressing, utilizes a targeted acid-anhydride bovine β-lactoglobulin blocking technology. It has obtained Class II Medical Device Registration Certification in China and is now widely used in hospitals and health channels across multiple provinces.
Research Collaborations
He Yuan Bio maintains close partnerships with top research institutions, including:
Shanghai Jiao Tong University
Fudan University
Tongji University
Nanjing University of Chinese Medicine
Henan University of Chinese Medicine
China Medical University
Together, they are advancing research on bioprotein materials for cervical cancer prevention. Their joint project, “Effectiveness Evaluation of Anti-HPV Gel Preparations in Community-Based Cervical Cancer Prevention,” has been officially approved by the National Health Commission’s Health Development Research Center, providing a solid foundation for evidence-based medical research on large-scale interventions.
Manufacturing Capabilities
He Yuan Bio shares access to Bebevisa’s world-class production infrastructure in the Wuhan Optics Valley Bio City, including:
5,000㎡ GMPc-certified production workshops
40,000㎡ intelligent warehousing center
10,000-level R&D labs (with full capabilities for physicochemical analysis, bacterial culture, microbiological testing, and positive control)
Modern 100,000-level GMP production base
16 fully automated intelligent production lines
From raw material extraction to finished product filling, the entire supply chain is vertically integrated. As an origin-based OEM/ODM manufacturer, He Yuan Bio helps partner brands reduce total costs by over 30%.
Track Record & Global Reach
With over 20 years of industry experience (including the group’s predecessor and core team), He Yuan Bio and its parent company have provided full lifecycle services to more than 230 brands, including:
Product ideation and positioning consulting
Custom R&D and formulation (anti-HPV, antimicrobial, disinfection, skincare, etc.)
Packaging design and procurement
Manufacturing and compliance testing
Medical device / disinfection product registration
Brand output and incubation
Marketing and cross-border go-to-market strategy
Sales & International Presence
He Yuan Bio’s sales channels cover hospitals, e-commerce, supermarkets, direct sales, and pharmaceutical companies. Products are exported to 76 countries, with over 50 million units sold globally. All products meet EU and FDA standards, giving the company a leading share in the international biomaterial and bioprotein dressing market.
Future Vision
Moving forward, He Yuan Bio will continue to leverage the strategic location and policy advantages of the Ezhou Cross-border E-commerce Industrial Park. Driven by “China Smart Manufacturing + Global Compliance,” the company aims to become a trusted one-stop source factory and brand accelerator in the global anti-HPV and biomedical materials sector.